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Synthesis and biological evaluation of tricyclic guanidine analogues of batzelladine K for antimalarial, antileishmanial, antibacterial, antifungal and anti-HIV activities.

Chemical biology & drug design

Ahmed N, Brahmbhatt KG, Khan SI, Jacob M, Tekwani BL, Sabde S, Mitra D, Singh IP, Khan IA, Bhutani KK.
PMID: 26404724
Chem Biol Drug Des. 2012 Jun 15; doi: 10.1111/j.1747-0285.2012.01427.x. Epub 2012 Jun 15.

Fifty analogues of batzelladine K were synthesized and evaluated for in vitro antimalarial (Plasmodium falciparum), antileishmanial (Leishmania donovani), antimicrobial (panel of bacteria and fungi), antiviral (HIV-1) activities. Analogues 14h and 20l exhibited potential antimalarial activity against chloroquine-sensitive D6 strain...

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Ahmed N, Brahmbhatt KG, Khan SI, et al. Synthesis and biological evaluation of tricyclic guanidine analogues of batzelladine K for antimalarial, antileishmanial, antibacterial, antifungal and anti-HIV activities. Chem Biol Drug Des. 2012;doi: 10.1111/j.1747-0285.2012.01427.x.
Ahmed, N., Brahmbhatt, K. G., Khan, S. I., Jacob, M., Tekwani, B. L., Sabde, S., Mitra, D., Singh, I. P., Khan, I. A., & Bhutani, K. K. (2012). Synthesis and biological evaluation of tricyclic guanidine analogues of batzelladine K for antimalarial, antileishmanial, antibacterial, antifungal and anti-HIV activities. Chemical biology & drug design, . https://doi.org/10.1111/j.1747-0285.2012.01427.x
Ahmed, Nafees, et al. "Synthesis and biological evaluation of tricyclic guanidine analogues of batzelladine K for antimalarial, antileishmanial, antibacterial, antifungal and anti-HIV activities." Chemical biology & drug design vol. (2012). doi: https://doi.org/10.1111/j.1747-0285.2012.01427.x
Ahmed N, Brahmbhatt KG, Khan SI, Jacob M, Tekwani BL, Sabde S, Mitra D, Singh IP, Khan IA, Bhutani KK. Synthesis and biological evaluation of tricyclic guanidine analogues of batzelladine K for antimalarial, antileishmanial, antibacterial, antifungal and anti-HIV activities. Chem Biol Drug Des. 2012 Jun 15; doi: 10.1111/j.1747-0285.2012.01427.x. Epub 2012 Jun 15. PMID: 26404724.
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Corrigendum.

Chemical biology & drug design

[No authors listed]
PMID: 26778111
Chem Biol Drug Des. 2016 Feb;87(2):312. doi: 10.1111/cbdd.12694.

No abstract available.

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Corrigendum. Chem Biol Drug Des. 2016;87(2):312doi: 10.1111/cbdd.12694.
(2016). Corrigendum. Chemical biology & drug design, 87(2), 312. https://doi.org/10.1111/cbdd.12694
"Corrigendum." Chemical biology & drug design vol. 87,2 (2016): 312. doi: https://doi.org/10.1111/cbdd.12694
Corrigendum. Chem Biol Drug Des. 2016 Feb;87(2):312. doi: 10.1111/cbdd.12694. PMID: 26778111.
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Retraction.

Chemical biology & drug design

[No authors listed]
PMID: 31342669
Chem Biol Drug Des. 2019 Jul;94(1):1422. doi: 10.1111/cbdd.13504. Epub 2019 Apr 22.

"Synthesis, Characterization, and In vitro Studies of PLGA-PEG Nanoparticles for Oral Insulin Delivery" DOI: https://doi.org/10.1111/cbdd.13504 by Sara Hosseininasab, Roghiyeh Pashaei-Asl, Amir Ahmad Khandaghi, Hamid Tayefi Nasrabadi, Kazem Nejati-Koshki, Abolfazl Akbarzadeh, Sang Woo Joo, Younes Hanifehpour & Soodabeh Davaran. The...

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Retraction. Chem Biol Drug Des. 2019;94(1):1422doi: 10.1111/cbdd.13504.
(2019). Retraction. Chemical biology & drug design, 94(1), 1422. https://doi.org/10.1111/cbdd.13504
"Retraction." Chemical biology & drug design vol. 94,1 (2019): 1422. doi: https://doi.org/10.1111/cbdd.13504
Retraction. Chem Biol Drug Des. 2019 Jul;94(1):1422. doi: 10.1111/cbdd.13504. Epub 2019 Apr 22. PMID: 31342669.
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Corrigendum.

Chemical biology & drug design

[No authors listed]
PMID: 30171676
Chem Biol Drug Des. 2018 Sep;92(3):1717. doi: 10.1111/cbdd.13382.

No abstract available.

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Corrigendum. Chem Biol Drug Des. 2018;92(3):1717doi: 10.1111/cbdd.13382.
(2018). Corrigendum. Chemical biology & drug design, 92(3), 1717. https://doi.org/10.1111/cbdd.13382
"Corrigendum." Chemical biology & drug design vol. 92,3 (2018): 1717. doi: https://doi.org/10.1111/cbdd.13382
Corrigendum. Chem Biol Drug Des. 2018 Sep;92(3):1717. doi: 10.1111/cbdd.13382. PMID: 30171676.
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Corrigendum.

Chemical biology & drug design

[No authors listed]
PMID: 30267486
Chem Biol Drug Des. 2018 Oct;92(4):1817. doi: 10.1111/cbdd.13402.

No abstract available.

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Corrigendum. Chem Biol Drug Des. 2018;92(4):1817doi: 10.1111/cbdd.13402.
(2018). Corrigendum. Chemical biology & drug design, 92(4), 1817. https://doi.org/10.1111/cbdd.13402
"Corrigendum." Chemical biology & drug design vol. 92,4 (2018): 1817. doi: https://doi.org/10.1111/cbdd.13402
Corrigendum. Chem Biol Drug Des. 2018 Oct;92(4):1817. doi: 10.1111/cbdd.13402. PMID: 30267486.
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Information Theoretic Approach in Allometric Scaling Relations of DNA and Proteins.

Chemical biology & drug design

Adiguzel Y.
PMID: 34855304
Chem Biol Drug Des. 2021 Dec 02; doi: 10.1111/cbdd.13988. Epub 2021 Dec 02.

Allometric scaling relations can be observed in between molecular parameters. Hence, we looked for presence of such relation among sizes (i.e., lengths) of proteins and genes. Protein-lengths exist in the literature as the number of amino acids. They can...

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Adiguzel Y. Information Theoretic Approach in Allometric Scaling Relations of DNA and Proteins. Chem Biol Drug Des. 2021;doi: 10.1111/cbdd.13988.
Adiguzel, Y. (2021). Information Theoretic Approach in Allometric Scaling Relations of DNA and Proteins. Chemical biology & drug design, . https://doi.org/10.1111/cbdd.13988
Adiguzel, Yekbun. "Information Theoretic Approach in Allometric Scaling Relations of DNA and Proteins." Chemical biology & drug design vol. (2021). doi: https://doi.org/10.1111/cbdd.13988
Adiguzel Y. Information Theoretic Approach in Allometric Scaling Relations of DNA and Proteins. Chem Biol Drug Des. 2021 Dec 02; doi: 10.1111/cbdd.13988. Epub 2021 Dec 02. PMID: 34855304.
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Extraction, structural characterization, and physicochemical properties of polysaccharide from purple sweet potato.

Chemical biology & drug design

Yang W, Huang G.
PMID: 34550642
Chem Biol Drug Des. 2021 Dec;98(6):979-985. doi: 10.1111/cbdd.13952. Epub 2021 Sep 26.

The polysaccharide from purple sweet potato (PPSP) was extracted. The structure was characterized and partial physicochemical properties were described of PPSP via UV, IR, NMR, XRD, DSC-TGA, LDS, and Congo red assay. This study provided a theoretical basis for...

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Yang W, Huang G. Extraction, structural characterization, and physicochemical properties of polysaccharide from purple sweet potato. Chem Biol Drug Des. 2021;98(6):979-985doi: 10.1111/cbdd.13952.
Yang, W., & Huang, G. (2021). Extraction, structural characterization, and physicochemical properties of polysaccharide from purple sweet potato. Chemical biology & drug design, 98(6), 979-985. https://doi.org/10.1111/cbdd.13952
Yang, Wenjian, and Huang, Gangliang. "Extraction, structural characterization, and physicochemical properties of polysaccharide from purple sweet potato." Chemical biology & drug design vol. 98,6 (2021): 979-985. doi: https://doi.org/10.1111/cbdd.13952
Yang W, Huang G. Extraction, structural characterization, and physicochemical properties of polysaccharide from purple sweet potato. Chem Biol Drug Des. 2021 Dec;98(6):979-985. doi: 10.1111/cbdd.13952. Epub 2021 Sep 26. PMID: 34550642.
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Synthesis and structure-activity relationship of L-methionine-coupled 1,3,4-thiadiazole derivatives with activity against influenza virus.

Chemical biology & drug design

Tatar E, Yaldız S, Kulabaş N, Vanderlinden E, Naesens L, Küçükgüzel İ.
PMID: 34873848
Chem Biol Drug Des. 2021 Dec 06; doi: 10.1111/cbdd.13995. Epub 2021 Dec 06.

In previous investigations, we identified a class of 1,3,4-thiadiazole derivatives with antiviral activity. N-{3-(Methylsulfanyl)-1-[5-(phenylamino)-1,3,4-thiadiazole-2-yl]propyl}benzamide emerged as a relevant lead compound for designing novel influenza A virus inhibitors. In the present study, we elaborated on this initial lead by performing...

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Tatar E, Yaldız S, Kulabaş N, et al. Synthesis and structure-activity relationship of L-methionine-coupled 1,3,4-thiadiazole derivatives with activity against influenza virus. Chem Biol Drug Des. 2021;doi: 10.1111/cbdd.13995.
Tatar, E., Yaldız, S., Kulabaş, N., Vanderlinden, E., Naesens, L., & Küçükgüzel, �. �. (2021). Synthesis and structure-activity relationship of L-methionine-coupled 1,3,4-thiadiazole derivatives with activity against influenza virus. Chemical biology & drug design, . https://doi.org/10.1111/cbdd.13995
Tatar, Esra, et al. "Synthesis and structure-activity relationship of L-methionine-coupled 1,3,4-thiadiazole derivatives with activity against influenza virus." Chemical biology & drug design vol. (2021). doi: https://doi.org/10.1111/cbdd.13995
Tatar E, Yaldız S, Kulabaş N, Vanderlinden E, Naesens L, Küçükgüzel İ. Synthesis and structure-activity relationship of L-methionine-coupled 1,3,4-thiadiazole derivatives with activity against influenza virus. Chem Biol Drug Des. 2021 Dec 06; doi: 10.1111/cbdd.13995. Epub 2021 Dec 06. PMID: 34873848.
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Synthesis and evaluation of diphyllin β-hydroxyl amino derivatives as novel V-ATPase inhibitors.

Chemical biology & drug design

Zhu L, Lu Y, Li Y, Ling Y, Zhao Y.
PMID: 34233089
Chem Biol Drug Des. 2021 Oct;98(4):674-682. doi: 10.1111/cbdd.13920. Epub 2021 Jul 29.

Natural diphyllin glycosides were identified as potent vacuolar H

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Zhu L, Lu Y, Li Y, et al. Synthesis and evaluation of diphyllin β-hydroxyl amino derivatives as novel V-ATPase inhibitors. Chem Biol Drug Des. 2021;98(4):674-682doi: 10.1111/cbdd.13920.
Zhu, L., Lu, Y., Li, Y., Ling, Y., & Zhao, Y. (2021). Synthesis and evaluation of diphyllin β-hydroxyl amino derivatives as novel V-ATPase inhibitors. Chemical biology & drug design, 98(4), 674-682. https://doi.org/10.1111/cbdd.13920
Zhu, Li, et al. "Synthesis and evaluation of diphyllin β-hydroxyl amino derivatives as novel V-ATPase inhibitors." Chemical biology & drug design vol. 98,4 (2021): 674-682. doi: https://doi.org/10.1111/cbdd.13920
Zhu L, Lu Y, Li Y, Ling Y, Zhao Y. Synthesis and evaluation of diphyllin β-hydroxyl amino derivatives as novel V-ATPase inhibitors. Chem Biol Drug Des. 2021 Oct;98(4):674-682. doi: 10.1111/cbdd.13920. Epub 2021 Jul 29. PMID: 34233089.
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Deciphering the detailed structure-activity relationship of coumarins as Monoamine oxidase enzyme inhibitors-An updated review.

Chemical biology & drug design

Koyiparambath VP, Prayaga Rajappan K, Rangarajan TM, Al-Sehemi AG, Pannipara M, Bhaskar V, Nair AS, Sudevan ST, Kumar S, Mathew B.
PMID: 34233082
Chem Biol Drug Des. 2021 Oct;98(4):655-673. doi: 10.1111/cbdd.13919. Epub 2021 Jul 26.

In the last few years, Monoamine oxidase (MAO) have emerged as a target for the treatment of many neurodegenerative diseases including anxiety, depression, Alzheimer's, and Parkinson's diseases. The MAO inhibitors especially selective and reversible inhibitors of either of the...

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Koyiparambath VP, Prayaga Rajappan K, Rangarajan TM, et al. Deciphering the detailed structure-activity relationship of coumarins as Monoamine oxidase enzyme inhibitors-An updated review. Chem Biol Drug Des. 2021;98(4):655-673doi: 10.1111/cbdd.13919.
Koyiparambath, V. P., Prayaga Rajappan, K., Rangarajan, T. M., Al-Sehemi, A. G., Pannipara, M., Bhaskar, V., Nair, A. S., Sudevan, S. T., Kumar, S., & Mathew, B. (2021). Deciphering the detailed structure-activity relationship of coumarins as Monoamine oxidase enzyme inhibitors-An updated review. Chemical biology & drug design, 98(4), 655-673. https://doi.org/10.1111/cbdd.13919
Koyiparambath, Vishal Payyalot, et al. "Deciphering the detailed structure-activity relationship of coumarins as Monoamine oxidase enzyme inhibitors-An updated review." Chemical biology & drug design vol. 98,4 (2021): 655-673. doi: https://doi.org/10.1111/cbdd.13919
Koyiparambath VP, Prayaga Rajappan K, Rangarajan TM, Al-Sehemi AG, Pannipara M, Bhaskar V, Nair AS, Sudevan ST, Kumar S, Mathew B. Deciphering the detailed structure-activity relationship of coumarins as Monoamine oxidase enzyme inhibitors-An updated review. Chem Biol Drug Des. 2021 Oct;98(4):655-673. doi: 10.1111/cbdd.13919. Epub 2021 Jul 26. PMID: 34233082.
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Preparation, structure, and properties of tea polysaccharide.

Chemical biology & drug design

Fan Y, Zhou X, Huang G.
PMID: 34265179
Chem Biol Drug Des. 2021 Jul 15; doi: 10.1111/cbdd.13924. Epub 2021 Jul 15.

Tea polysaccharide is a kind of acid glycoprotein complex extracted from tea. Tea polysaccharide has a variety of biological activities, especially the hypoglycemic effect is outstanding. It is good for human health. Tea polysaccharides have been extensively studied over...

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Fan Y, Zhou X, Huang G. Preparation, structure, and properties of tea polysaccharide. Chem Biol Drug Des. 2021;doi: 10.1111/cbdd.13924.
Fan, Y., Zhou, X., & Huang, G. (2021). Preparation, structure, and properties of tea polysaccharide. Chemical biology & drug design, . https://doi.org/10.1111/cbdd.13924
Fan, Yumin, et al. "Preparation, structure, and properties of tea polysaccharide." Chemical biology & drug design vol. (2021). doi: https://doi.org/10.1111/cbdd.13924
Fan Y, Zhou X, Huang G. Preparation, structure, and properties of tea polysaccharide. Chem Biol Drug Des. 2021 Jul 15; doi: 10.1111/cbdd.13924. Epub 2021 Jul 15. PMID: 34265179.
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Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates.

Chemical biology & drug design

Gagné-Boulet M, Bouzriba C, Chavez Alvarez AC, Fortin S.
PMID: 34623027
Chem Biol Drug Des. 2021 Oct 08; doi: 10.1111/cbdd.13971. Epub 2021 Oct 08.

We prepared and biologically evaluated 32 novel molecules named phenyl 4-(dioxoimidazolidin-1-yl)benzenesulfonates (PID-SOs) and ethyl 2-(3-(4-(phenoxysulfonyl)phenyl)ureido)acetates (EPA-SOs). The antiproliferative activity of PID-SOs and EPA-SOs was assessed on four cancer cell lines (HT-1080, HT-29, M21, and MCF7). The most potent PID-SOs...

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Gagné-Boulet M, Bouzriba C, Chavez Alvarez AC, et al. Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates. Chem Biol Drug Des. 2021;doi: 10.1111/cbdd.13971.
Gagné-Boulet, M., Bouzriba, C., Chavez Alvarez, A. C., & Fortin, S. (2021). Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates. Chemical biology & drug design, . https://doi.org/10.1111/cbdd.13971
Gagné-Boulet, Mathieu, et al. "Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates." Chemical biology & drug design vol. (2021). doi: https://doi.org/10.1111/cbdd.13971
Gagné-Boulet M, Bouzriba C, Chavez Alvarez AC, Fortin S. Preparation and biological evaluation of new antimicrotubule agents: Modification of the imidazolidin-2-one moiety of phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates. Chem Biol Drug Des. 2021 Oct 08; doi: 10.1111/cbdd.13971. Epub 2021 Oct 08. PMID: 34623027.
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Showing 1 to 12 of 216 entries